Product overview
High-performance reversed-phase HPLC column with excellent peak shape and reproducibility for pharmaceutical and general analytical applications
Key features
- Exceptional peak shape for basic compounds
- High carbon load (18% C)
- Wide pH range (1.5-10)
- USP L1 classification
- Excellent lot-to-lot reproducibility
Technical specifications
Applications
- Pharmaceutical QC and method development
- Impurity profiling
- Natural product analysis
- Small molecule separation
- USP/EP monograph methods
Technical details
Column Chemistry
Luna C18(2) features a high-density bonded phase with superior double-endcapping, resulting in exceptional peak symmetry even for challenging basic compounds. The high purity silica substrate provides consistent selectivity across production lots.
Performance Characteristics
Designed for reproducible separations, Luna C18(2) offers excellent retention for non-polar to moderately polar compounds. The column exhibits minimal peak tailing for amines and maintains stability across a wide pH range, making it ideal for method transfer and validation.
Recommended Operating Conditions
Flow rate: 1.0 mL/min (4.6mm ID), Mobile phase: Acetonitrile/water or methanol/water with buffers (phosphate, acetate, TFA). Compatible with 100% aqueous mobile phases when properly equilibrated.
Ordering information
| Part Number | Description | Lead Time |
|---|---|---|
| 00G-4252-E0 | Luna C18(2) 5μm, 250 x 4.6mm | 2-3 weeks |
| 00G-4252-N0 | Luna C18(2) 5μm, 150 x 4.6mm | 2-3 weeks |